Protein Purification Reagents and Kits
Genscript Corporation CD4/LEU3 Biotin His Avi
CD4 also known as L3T4 T4 and W3/25 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes It is a standard phenotype marker for the identification of T cell populations Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses In T-cells functions primarily as a coreceptor for MHC class II molecule peptide complex
Cayman Chemical 5-chloro nI 10mg
A derivative of NNEI that has a chloride atom added to the terminal carbon of the pentyl group; intended for forensic and research applications
Genscript Corporation CD46 His Canine
CD46 was discovered in 1986 during a search for novel C3b-binding proteins CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated self-attack
Genscript Corporation TROP-2/TACSTD2 His Cynomolgu
Trop-2 also known as epithelial glycoprotein-1 antigen (EGP-1) is a protein that in humans is encoded by the TACSTD2 gene Mutations of this gene result in gelatinous drop-like corneal dystrophy an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness
Genscript Corporation MSLN/Mesothelin296-598 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally
Genscript Corporation CD14 His Mouse
CD14 is a glycosylphosphatidylinositol (GPI)-anchored receptor known to serve as a co-receptor for several Toll-like Receptors (TLRs) both at the cell surface and in the endosomal compartment CD14 can be expressed by cells of both hematopoietic and non-hematopoietic origin as a cell membrane or secreted protein
Cayman Chemical 5-chloro nI 5mg
A derivative of NNEI that has a chloride atom added to the terminal carbon of the pentyl group; intended for forensic and research applications
Genscript Corporation GITR/TNFRSF18Biotin His A
GITR (glucocorticoid-induced tumor necrosis factor receptor) also known as AITR and TNFRSF18 is a 40 kDa transmembrane glycoprotein that functions in immune regulation GIRT is a receptor for TNFSF18 Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death Mediated NF-kappa-B activation via the TRAF2/NIK pathway
Genscript Corporation MSLN/Mesothelin298-600 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF)
Cayman Chemical 5fluoro nI 2naphthyl Iso 10mg
A derivative of NNEI with a fluorine atom at the terminal carbon of the pentyl chain and the naphthyl group joined at the 2 rather than 1 position; intended for forensic and research applications
AdipoGen Asprosin human rec His
Recombinant protein. Human asprosin aa 2732-2871 is fused at the C-terminus to a His-tag. Source E. coli. Lyophilized from 0.2µm-filtered solution in 50mM Tris-HClpH 8.2, 200mM NaCl. Asprosin is a new fasting-induced protein hormone that targets the liver to increase plasma glucose levels. Asprosin is the C-terminal cleavage product of the protein pro-Fibrillin-1. Asprosin is secreted from white adipose tissue and increases hepatic glucose production by using cAMP as a second messenger, leading to activation of protein Kinase A. Reduction of Asprosin levels protects against metabolic syndrome-associated hyperinsulinism. Asprosin may act as a circulating hunger signal. Indeed, peripherally injected recombinant asprosin can cross the blood-brain barrier and intracerebroventricular i.c.v. injection of recombinant asprosin stimulated appetite in wild-type mice, indicating a central mechanism of action.
AdipoGen IL-37 human rec His
Protein. Human IL-37 aa 1-218 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Purity >95% SDS-PAGE. IL-37 IL-1F7 IL-1H4 is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells PBMCs and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor IL-18R and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide LPS-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
Genscript Corporation MSLN/Mesothelin296-598 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally